Andreessen Horowitz (a16z) Investment Report: Key 2024–2025 Sectors and Companies

Posted on October 05, 2025 at 06:20 PM

Andreessen Horowitz (a16z) Investment Report: Key 2024–2025 Sectors and Companies


🧠 AI & Machine Learning

2025 Investments

  • Periodic Labs: A $300M Series A investment in AI-driven autonomous labs for breakthroughs in physics, chemistry, and materials science. (a16z.com)
  • Phota Labs: $5.6M Seed Round investment in generative AI that preserves likeness and authenticity in photos. (a16z.com)
  • Sola: AI-native process automation platform enabling users to create and maintain intelligent agents. (a16z.com)
  • Rillet: AI-native ERP system designed for speed, intelligence, and automation. (a16z.com)
  • Salient: AI-first workflow automation platform for lenders, handling borrower interactions across voice, text, email, and chat. (a16z.com)

2024 Investments

  • Aerodome, Air Space Intelligence, AKASA, Alchemy Health, Alleviate Health, Amber, Ambience Healthcare, Ambient.ai, Anyscale, Applied Intuition (a16z.com)

💰 Fintech

2025 Investments

  • Crux: Innovative solutions in banking, lending, insurance, and real estate. (a16z.com)

2024 Developments

  • Fintech DevCon highlights growth in developer-focused fintech solutions. (a16z.com)

🛡️ American Dynamism

2025 Investments

  • Apex Space: Contributing to dynamic U.S. economic growth and innovation. (a16z.com)
  • Anduril: AI-powered defense systems and resilient energy infrastructure. (a16z.com)

2024 Highlights

  • American Dynamism 50 project identified 50 companies strengthening U.S. competitiveness across aerospace, defense, energy, and manufacturing. (a16z.com)

🧾 Summary

Andreessen Horowitz’s 2024–2025 investments demonstrate a focus on AI, automation, fintech, and American innovation. The portfolio emphasizes efficiency, creativity, and enterprise transformation across emerging technologies.

More details: https://a16z.com/news-content/